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InterPlexus Seriphos Adrenal Support Main Label
InterPlexus Seriphos Adrenal Support Supplement Facts
InterPlexus Seriphos Adrenal Support Caution Statement
InterPlexus Seriphos Adrenal Support Combination


Phosphorylated Serine | Original Formula

Regular price $37.99
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Capsules per Bottle:    100

Capsules per Serving:  1

Servings per Bottle:     100

Suggested Use

Take 1 capsule daily with water 15 minutes before a meal or as directed by your physician.


If pregnant or nursing, consult your physician before using this or any other product. Keep out of reach of children.


1000 mg proprietary blend of Phosphorylated Serine/Ethanolamine.

Other Ingredients

Magnesium Stearate (palm vegetable), Cellulose, Vegetarian Capsule Shell (hypromellose, water).


The original formulation of our most popular supplement. Seriphos™ provides superior adrenal support and is intended to calm anxiety and help with stress management.* The benefits of being less stressed and less anxious often include a better and more restful night’s sleep and improved overall quality of life.

Stress affects the body in a number of ways, both positively and negatively. Exposure to chronic stress at any level and regardless of the type of stress is considered negative stress. Chronic stress may adversely affect your health by elevating your cortisol levels beyond what is necessary. This can leave you feeling stressed and feeling overwhelmed as your body’s fight or flight response is triggered at improper times, often before bed. Seriphos works by helping to lower cortisol levels when they are elevated, helping to reduce the effects of negative stress.*

Seriphos is formulated to promote healthy cortisol output during times of chronic and acute stress which may help reduce the effects of adrenal fatigue.* Elevated cortisol levels can lead to other significant health problems including adrenal fatigue. Adrenal fatigue may occur when the adrenal glands are asked to work overtime and the adrenal system is pushed beyond its limits. 

Seriphos helps improve your quality of life by promoting healthy adrenal function and helping your body respond better to stress.* Seriphos is intended to support your adrenal glands. It provides your body with the building blocks it needs to make its own phosphatidylserine and phosphatidylethanolamine. These two nutrients are key components of the cell membrane and help regulate essential aspects of cellular function. 

To learn more about the benefits of supplementation with Seriphos™ click here.

Customer Reviews

Based on 25 reviews
Anne Hickok


Fantastic product!

I have been taking Seriphos for years. My doctor recommended it a few years ago for anxiety. It's a wonderful product and it really does help.

Dyan Brown

Finally getting some sleep

Bonnie Carbone
High cortisol levels

I had a very bad reaction to a steroid while having Covid. My cortisol levels were very high - I felt manic, I could not sleep, I had a very high heart rate and I had unbelievable anxiety running rampant throughout my body. My doctor suggested taking this, 4 pills a day, two in the morning and two before bed. It worked the first day pretty well, second day even better and third day was great. I kept taking it for 4 months and my cortisol levels evened out. Now I don’t need to take it but I will sometimes if I want a deep sleep. It’s honestly the best supplement I’ve ever tried. Another doctor was prescribing me anti-anxiety medication and that wasn’t doing anything. I’m a big proponent of natural remedies so this is the best option in my book.

Jackie Deans