Thyroid Support for healthy thyroid hormone output and function*
Thyro-DyneTM provides iodine; targeted amino acids, including L-tyrosine; and herbal extracts of Ashwagandha and guggul.
This formula works by providing the precursors, co-factors, and botanicals research has shown to support optimal thyroid function by increasing thyroid hormone (T3 and T4) levels, thyroid hormone production, and thyroid hormone function.*
Thyro-DyneTM contains iodine, L-tyrosine, L-cysteine, Ashwagandha, and guggul.
What the Research and Clinical Use Shows:
Iodine consumption appears to be decreasing in the United States, potentially putting individuals at risk for an iodine deficiency.1,2 Decreasing levels are likely due to decreased intake of iodized salt and other dietary trends. Iodine is necessary to maintain thyroid hormone levels as iodine is required to produce T4 and T3.
Tyrosine, another precursor for thyroid hormones, is also vital in their production. In an animal study, diets deficient in tyrosine and phenylalanine (an amino acid precursor for tyrosine) caused significant deficits in thyroid hormone production.3
In animal studies, diets deficient in cysteine decrease active thyroid hormone production.4 Researchers hypothesize that aging and its associated problems may be linked to deficient cysteine intake, and current diets may be suboptimal for maintaining cysteine levels as we age.5
Ashwagandha (Withania somnifera)
This herb has a long history of use in Ayurvedic medicine. Notably, one clinical study shows that Ashwagandha may increase thyroid hormone production.6 Similar results from an animal study found that Ashwagandha increased thyroid hormone levels.7
Guggul (Commiphora mukul)
Guggul is another Ayurvedic herb that increased thyroid hormone production in several animal studies.8-10
1 Stagnaro-Green A, Dogo-Isonaige E, Pearce EN, et al. Marginal iodine status and high rate of subclinical hypothyroidism in Washington DC women planning conception. Thyroid. 2015;25(10):1151-4. doi:10.1089/thy.2015.0063
2 Hollowell JG, Staehling NW, Hannon WH, et al. Iodine nutrition in the United States. Trends and public health implications: iodine excretion data from National Health and Nutrition Examination Surveys I and III (1971-1974 and 1988-1994). J Clin Endocrinol Metab. 1998;83(10):3401-8.
3 Elkin RG, Featherston WR, Rogler JC. Effects of dietary phenylalanine and tyrosine on circulating thyroid hormone levels and growth in the chick. J Nutr. 1980;110(1):132-8.
4 Garcin H, Suberville C, Higueret P, et al. Changes in glutathione status and 3,5,3'-triiodothyronine action in livers of rats given cysteine-deficient diets. Br J Nutr. 1989;61(2):301-7.
5 Dröge W. Oxidative stress and ageing: is ageing a cysteine deficiency syndrome? Philos Trans R Soc Lond, B, Biol Sci. 2005;360(1464):2355-72.
6 Gannon JM, Forrest PE, Roy Chengappa KN. Subtle changes in thyroid indices during a placebo-controlled study of an extract of Withania somnifera in persons with bipolar disorder. J Ayurveda Integr Med. 2014;5(4):241-5.
7 Panda S, Kar A. Changes in thyroid hormone concentrations after administration of ashwagandha root extract to adult male mice. J Pharm Pharmacol.
8 Panda S, Kar A. Guggulu (Commiphora mukul) potentially ameliorates hypothyroidism in female mice. Phytother Res. 2005;19(1):78-80.
9 Panda S, Kar A. Gugulu (Commiphora mukul) induces triiodothyronine production: possible involvement of lipid peroxidation. Life Sci. 1999;65(12):PL137-41.
10 Tripathi YB, Malhotra OP, Tripathi SN. Thyroid stimulating action of Z-guggulsterone obtained from Commiphora mukul. Planta Med. 1984;50(1):78-80.